Ozonetherapy using the techniques of small self-emo-infusion, and the topical application of ozonated oils or irrigation with ozonated water at the nasal level, could help to enhance the innate immune response at the level of the entrance ports in order to decrease the viral load and slow viral growth, especially in the early stages. In fact, recent studies show that nasal transport is likely to be a key feature of transmission, and drugs / vaccines administered intranasally could be highly effective in limiting spread